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Students' pubblications - Years 2009-10

Pubblications in peer reviewed journals (pubblished or accepted)

 

1.      Barinov, A., Malcioǧlu, O.B., Fabris, S., Sun, T., Gregoratti, L., Dalmiglio, M., Kiskinova, M. Initial stages of oxidation on graphitic surfaces: Photoemission study and density functional theory calculations, 2009, Journal of Physical Chemistry C 113 (21), pp. 9009-9013

2.      Bozzini, B., Dalmiglio, M., De Gaudenzi, G.P., D'Urzo, L., Gregoratti, L. An investigation of the corrosion of WC-Co cermets in CN--containing aqueous solutions. Part II: Synchrotron-based high lateral-resolution XPS study, 2009, Corrosion Science 51 (8), pp. 1675-1678

3.      M. Dalmiglio, M. Amati, L. Gregoratti, T. O. Menteş, M. A. Niño, L. Felisari and M. Kiskinova, Catalytic activity of PtRh particles, submitted to Journal of Physical Chemistry, 2010

4.      P. Lacovig, M. Pozzo, D. Alfè, P. Vilmercati, A. Baraldi, S. Lizzit, Growth of Dome-Shaped Carbon Nanoislands on Ir(111): The Intermediate between Carbidic Clusters and Quasi-Free-Standing Graphene, Phys. Rev. Lett. 103, 166101 (2009)

5.             E. Golfetto, A. Baraldi, M. Pozzo, D. Alfè, A. Sala, P. Lacovig, E. Vesselli, S. Lizzit, G. Comelli, R. Rosei, Determining the chemical reactivity trends of Pd/Ru(0001) pseudomorphic overlayers: core level shift measurements and DFT calculations, J. Phys. Chem. C, in press DOI: 10.1021/jp908568v, 2010

6.      T. Montini, A. Speghini, L. De Rogatis, B. Lorenzut, M. Bettinelli, M. Graziani and P. Fornasiero, “The identification of the structural phases of CexZr1-xO2 by Eu(III) luminescence studies.”, Journal of the American Chemical Society 131 (2009), 13155-13160

7.      S. Specchia, L. D. Vella, B. Lorenzut, T. Montini, V. Specchia and P. Fornasiero, “Effect of the catalyst load on syngas production in SCT-CPO reactors.”, Industrial and Engineering Chemistry Research (2009), accepted for publication, doi:10.1021/ie900695j.

8.      L. De Rogatis, M. Cargnello, V. Gombac, B. Lorenzut, T. Montini and P. Fornasiero, “Embedded phases: a way to active and stable catalysts”, ChemSusChem (2009), accepted for publication

9.      E. Conca, T. Negri, A. Gronchi, E. Fumagalli, E. Tamborini, G.M. Pavan, M. Fermeglia, M.A. Pierotti, S. Pricl, S. Pilotti. Activate and resist: L576P-KIT in GIST. Molecular Cancer Therapeutics. Mol Cancer Ther 1535-7163.MCT-09-0662. Mol Cancer Ther 8(9):2491-5, 2009.

10.  S.E. Woodman, J.C. Trent, K. Stemke-Hale, A.J. Lazar, S. Pricl, G.M. Pavan, M. Fermeglia, Y.N. Gopal, D. Yang, D.A. Podoloff, D. Ivan, K.B. Kim, N. Papadopoulos, P. Hwu, G.B. Mills and M.A. Davies. Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates. Mol Cancer Ther 8(8):2079-85, 2009.

11.  T. Negri, G.M. Pavan, S. Pricl, S. Lagonigro, F. Miselli, A. Greco,  M. Fermeglia, M.A. Pierotti, S. Pilotti, E. Tamborini, T670X KIT mutations in GISTs: making sense of missense. J Natl Cancer Inst 2009;101:1–11.

12.  S.E. Woodman, J.C. Trent, K. Stemke-Hale, A. Lazar, S. Pricl, G.M. Pavan, N. Papadopoulos, P. Hwu, G.B. Mills, M.A. Davies. Selective Activity of Dasatinib for the Most Common KIT Mutation in Melanoma (L576P). Journal of Clinical Oncology, 2009 ASCO Annual Meeting Proceedings (Post-Meeting Edition). Vol 27, No 15S (May 20 Supplement), 2009: 9019.

13.  Toth R, Voorn DJ, Handgraaf JW, Fraaije JGEM, Fermeglia M, Pricl S, Posocco P. Multiscale computer simulation studies of water-based montmorillonite/poly(ethylene oxide) nanocomposites. Macromolecules, 2009, on web (ma200901584w).

14.  Scocchi G, Posocco P, Handgraaf JW, Fraaije JGEM, Fermeglia M, Pricl S. A complete multiscale modelling approach for polymer-clay nanocomposites. Chemistry - A European Journal, 15, 7586-7592, 2009.

15.  Posocco P, Lisal M, Posel Z, Fermeglia M, Pricl S. A multiscale molecular simulation approach to the prediction of the morphology of self-assembled nanoparticles in diblock copolymers. Journal of Physical Chemistry B, submitted.

16.  Posocco P, Fermeglia M, Pricl S. A multiscale toolbox for morphology prediction of diblock copolymers for drug delivery. Biomacromolecules, submitted.

17.  Pricl S, Posocco P, Scocchi G, Fermeglia M. “Polymer-clay nanocomposites”, in Handbook of Nanophysics, Klaus Sattler Editor, Taylor&Francis Publisher, 2009.

18.  Polyol Synthesis of Silver Nanoparticles: Mechanism of Reduction by Alditol Bearing Polysaccharides (Ivan Donati, Andrea Travan, Chiara Pelillo, Anna Coslovi, Alois Bonifacio,Valter Sergo, Sergio Paoletti). Biomacromolecules, 2009, 10 (2), 210-213

19.  Non-Cytotoxic Silver Nanoparticle – Polysaccharide Nanocomposites with Antimicrobial Activity (Andrea Travan, Chiara Pelillo, Ivan Donati, Eleonora Marsich,  Monica Benincasa, Tommaso Scarpa, Sabrina Semeraro, Gianluca Turco, Renato Gennaro, Sergio Paoletti). Biomacromolecules 2009, 10, 1429–1435

20.  Surface Modification and Polysaccharide Deposition on BISGMA/TEGDMA Thermosets (Andrea Travan, Ivan Donati,  Eleonora Marsich,  Francesca Bellomo,  Satish Achanta, Sabrina Semeraro,  Tommaso Scarpa,  Mila Toppazzini,  Vittorio Spreafico, and Sergio Paoletti). Biomacromolecules 2010. (DOI: 10.1021/bm9011419)

21.  Silver-Polysaccharide Nanocomposite Antimicrobial Coatings for Methacrylic Thermosets (Andrea Travan, Eleonora Marsich, Ivan Donati, Monica Benincasa, Marta Giazzon, Laura Felisari, Sergio Paoletti. Submitted to European Cells and Materials Journal (2010)

22.  Characterization of silver nanoparticles for biomedical applications by means of quantitative analysis of TEM micrographs (Francesco Brun, Andrea Travan, Agostino Accardo, Sergio Paoletti). Biomedical Sciences Instrumentation 2010 (In press).

23.  Silver nanocomposites and their biomedical applications (Andrea Travan, Eleonora Marsich, Ivan Donati, Sergio Paoletti). Chapter of the book entitled “Nanocomposites for the Life Sciences”. In press, Wiley-VCH (2010)

24.  Journal of Materials Science, “Raman investigation of the ageing of Ni-BaTiO3 multilayer ceramic capacitors”, A.Umeri, T.A. Kuku, N.Scuor and V.Sergo, Volume 43, Issue 3, P.922-926,2008-02-01, DOI  - 10.1007/s10853-007-2215-4, 2010

25.  L. Rigon, F. Arfelli, A. Astolfo, A. Bergamaschi, D. Dreossi, R. Longo, R.H. Menk, B. Schmitt, E. Vallazza, E. Castelli, “A single-photon counting “edge-on” silicon detector for synchrotron radiation mammography”, Nucl. Instr. And Meth. A, 608, S62-S65, 2009

26.  Alginate/Hydroxyapatite biocomposite for bone ingrowth: a trabecular structure with high and isotropic connectivity.Turco G, Marsich E, Bellomo F, Semeraro S, Donati I, Brun F, Grandolfo M, Accardo A, Paoletti S. Biomacromolecules. 2009 Jun 8; 10(6):1575-83

27.  Surface modification and polysaccharide deposition on BISGMA/TEGDMA based resins. Donati I., Travan A., Marsich E., Bellomo F., Achanta S., Semeraro S., Scarpa T., Toppazzini M., Spreafico V., Paoletti S. Submitted to Biomacromolecules, 2010

28.  Giovanni Birarda, Gianluca Grenci, Luca Businaro, Benedetta Marmiroli, Sabrina Pacor, Lisa Vaccari - “Fabrication of a microfluidic platform for investigating dynamic biochemical processes in living samples by FTIR microspectroscopy – Microelectronic Engineering (in press), 2010

29.  Giovanni Birarda, Gianluca Grenci, Luca Businaro, Benedetta Marmiroli, Sabrina Pacor, Federica, Piccirilli, Lisa Vaccari -  Infrared microspectroscopy of biochemical response of living cells in microfabricated devices” – Vibrational Spectroscopy (submitted - evaluated) 2009

30.  D’Amelio N, Fontanive L, Uggeri F, Suggi-Liverani F, Navarini L. NMR reinvestigation of the caffeine-chlorogenate complex in acqueous solution and in coffee brews. Food Biophys. 2009, 4, 321-330.

31.  Cadenaro M, Marchesi G, Antoniolli F, Davidson CL, De Stefano Dorigo E, Breschi L. “Flowability of composites is no guarantee for contraction stress reduction.” Dental Materials 2009;25(5):649-54.

32.  Mazzoni A, Marchesi G, Cadenaro M, Mazzotti G, Di Lenarda R, Ferrari M, Breschi M. “Push-out stress for fiber posts luted using different adhesive strategies.” European Journal Oral Science 2009;117(4):447-453.

33.  Cadenaro M, Pashley DH, Marchesi G, Carrihlo M, Antoniolli F, Mazzoni A, Tay FR, Di Lenarda R, Breschi L. “Influence of chlorexidine on the degree of conversion and E-modulus of experimental adhesive blends”. Dental Materials 2009;25(5):1269-74.

34.  Marchesi G, Breschi L, Antoniolli F, De Stefano Dorigo E, Ferracane J, Cadenaro M. “Contraction stress of composite materials with different polymerization reactions assayed by low-and high-compliance systems. Dental Materials submitted, 2010.

35.  Breschi L, Cadenaro M, Mazzoni A, Navarra CO, Marchesi G, Di Lenarda R, De Stefano Dorigo E. “La durata del legame adesivo:la nuova sfida dell’ odontoiatria resteurativa.” Dentista Moderno 2009;4:41-54.

36.  “Dependence of the fractional anisotropy in cervical spine from the number of diffusion gradients, repeated acquisition and voxel size”, Santarelli, X., Garbin, G., Ukmar, M., Longo, R.; Magnetic Resonance Imaging (in press), 2010

37.  1) V. Gombac, L. Sordelli, T. Montini, J. J. Delgado, A. Adamski, G. Adami, M. Cargnello, S. Bernal and P. Fornasiero, “CuOx-TiO2 Photocatalysts for H2 Production from Ethanol and Glycerol Solutions.”, The Journal of Physical Chemistry A, in press, doi:10.1021/jp907242q, 2010.

38.  2) L. De Rogatis, M. Cargnello, V. Gombac, B. Lorenzut, T. Montini and P. Fornasiero, “Embedded phases: a way to active and stable catalysts.”, ChemSusChem, in press, 2010.

39.  3) M. Cargnello, T. Montini, S. Polizzi, N. L. Wieder, R. J. Gorte, M. Graziani and P. Fornasiero, “Novel embedded Pd@CeO2 catalysts: a way to active and stable catalysts.”, Dalton Transactions, in press, 2010.

40.  1) M. Cargnello, N. L. Wieder, T. Montini, R. J. Gorte and P. Fornasiero, “Synthesis of dispersible Pd@CeO2 core-shell nanostructures by self-assembly”, Journal of the American Chemical Society, submitted.

41.  The evolutionary conserved gene C16orf35 encodes a nucleo-cytoplasmic protein that interacts with p73.” Lunardi A, Chiacchiera F, D'Este E, Carotti M, Dal Ferro M, Di Minin G, Del Sal G, Collavin L. Biochem Biophys Res Commun. 2009 Oct 16;388(2):428-33.

42.  Corona G, Elia C, Casetta B, Diana C, Rosalen S, Bari M, Toffoli G. A liquid chromatography-tandem mass spectrometry method for the simultaneous determination of exemestane and its metabolite 17-dihydroexemestane in human plasma. J Mass Spectrom. 2009 Jun.

43.  Corona G, De Lorenzo E, Elia C, Simula MP, Avellini C, Baccarani U, Lupo F, Tiribelli C, Colombatti A, Toffoli G. Differential protomi analysis of hepatocellular carcinoma. Internation Journal of Oncology 2009 (accepted for publication)

44.  Migliorini E., Ban J., Di Foggia V., Ruaro ME., Torre V., Pozzato A., Grenci G., Tormen M, Lazzarino M. Effect of nanopatterned substrates on growth cones activity. Eur Biophys .J. 2009 Oct, (suppl 1) S89 

45.  Kondra S, Laishram J., J. Ban J.,Migliorini E., Di Foggia V., Lazzarino M., Torre V., Ruaro M.E. Integration of Confocal and Atomic Force Microscopy. Journal of Neuroscience methods. 2009 Feb 15;177(1):94-107. Epub 2008 Oct 18.

46.  Laishram J., Kondra S., Avossa D., Migliorini E., Lazzarino M., Torre V. A morphological analysis of growth cones of DRG neurons combining Atomic Force and Confocal Microscopy. Journal of Structural Biology. 2009 Sept.

47.   R.Muscia, G.Sciuto, F. Zuddas – On the usage of PCM elements within asphalt concrete to avoid ice formation on roadways. International Journal of Solar Energy, submitted 2010.

Pubblications in conference proceedings (national or international)

 

48.  POSTER - P. Lacovig, M. Pozzo, D. Alfè, P. Vilmercati, A. Baraldi, and S. Lizzit, Graphene Growth on Ir(111): A Fast XPS Study - CINF-DTU Summer School on “Reactivity of nanoparticles for more efficient and sustainable energy production”, Sandbjerg Gods (Denmark), 2009

49.         POSTER –  P. Lacovig, A. Baraldi, S. Lizzit, Chemical reactivity of nanoclusters deposited on solid surfaces: new time-domain and enhanced surface-sensitivity of photoelectron spectroscopy - Joint Workshop of SFB762 & IMPRS on “Magnetic properties of oxidic and multiferroic systems”, Wittenberg (Germany), 2009

50.  Posocco P, Fermeglia M, Pricl S. Multiscale molecular modeling of di/triblock copolymers for drug delivery. FOMMS, Blaine, USA, (2009).

51.  Fermeglia M, Posocco P, Pricl S, Fraaije JGEM, Handgraaf JW, Scocchi G, Danani A. A complete multiscale modeling approach for nanocomposites. Eurofillers, Alessandria, Italy, (2009).

52.  Fermeglia M, Posocco P, Pricl S, Fraaije JGEM, Handgraaf JW, Deglmann P, Kurkal-Siebert V,  Weiss H. On the DPD Parameter Estimation From Atomistic/Quantum Mechanics Information. AIChE Annual meeting, Nashville, USA, (2009).

53.  Fermeglia M, Scocchi G, Pricl S, Handgraaf JW, Fraaije JGEM, Posocco P. A Complete Multiscale Modeling Approach for Polymer-Clay Nanocomposites. AIChE Annual meeting, Nashville, USA, (2009).

54.  Posocco P, Fermeglia M, Pricl S. The Long and Winding Road. Multiscale Molecular Modeling Approach to the Self-Assembly of Di/Triblock Copolymers for Drug Delivery in Aqueous Solution. AIChE Annual meeting, Nashville, USA, (2009).

55.  Posocco P. Modellistica molecolare multiscala per la progettazione di materiali nanostrutturati. I giovani e la chimica in FVG, Trieste, (2009).

56.  G.M. Pavan, P. Posocco, M. Fermeglia, G. Scocchi, A. Malek, M.Maly, A. Danani, C. Catapano, S. Pricl. Nanocarriers in delivery of small interfering RNA theurapetics. 9th International Conference on Chemical and Process Engineering. Rome, 10-13 May 2009.

57.  POSTER - “Nanostructured Zirconia in dental applications: new problems for an old material” – A.Umeri, A. Bonifacio and V. Sergo – National Nanomedicine Conference – 28,29 November 2008 - Genova

58.  Spatio-Temporal Radiation Biology: Transdiscipinary Advances for Biomedical Applications – Booklet of abstracts (Saint Feliu de Guixols, Spain, 16-21 May 2009), A. Astolfo, R.-H. Menk, F. Arfelli, E. Schultke, C. Hall, L. Rigon, B.H.J. Juurlink, “Long Term Cell Tracking in Small Animals Phase Using Phase Contrast Based Micro CT and Synchrotron Radiation”, P.53.

59.  “POROUS NANO-HYDROXYAPATITE/ALGINATE SCAFFOLDS FOR BONE REGENERATION”  Eleonora Marsich, Sabrina Semeraro, Gianluca Turco, Francesca Bellomo, Ivan Donati and Sergio Paoletti (7-9 novembre 2008 Bone-tec Hannover; Joint Workshop of SFB762 & IMPRS 10th/11thSeptember 2009 in the Leucorea at Wittenberg)

60.  “SPERIMENTAZIONE IN VIVO DI SCAFFOLD DI ALGINATO E IDROSSIAPATITE PER RIGENERAZIONE OSSEA” F. Bellomo, M. Biasotto, G.Turco, R. Di Lenarda, S. Paoletti  (22° riunione nazionale “A. Castellani” dei dottorandi di ricerca in discipline biochimiche Brallo di Pregola (PV) 9 – 12 Giugno 2009;  Collegio dei docenti di odontoiatria Roma 22-24 aprile 2009)

61.  The Proceedings of Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2009), Giovanni Birarda,Gianluca Grenci, Luca Businaro, Benedetta Marmiroli, Giuseppe Bellisola and Lisa Vaccari, Single Living Cell Biochemical Rearrangements Investigated By Infrared Microspectroscopy In Microfluidic Devices - 978-0-9798064-2-1/μTAS2009/$20ⓒ2009CBMS pp 338-341.

62.  Marchesi G, Cadenaro M, Antoniolli F, Di Lenarda R, Pashley DH, Breschi L. “Influenza della clorexidina sul grado di conversione e sul modulo elastico in adesivi sperimentali.” Acts of  XIII national meeting SIDOC-Rome 19-21/2/2009.

63.  Marchesi G, Breschi L, Antoniolli F, De Stefano Dorigo E, Cadenaro M. “Stress da polimerizzazione di una resina a base siloranica.”Acts of national meeting  Docenti di Odontoiatria e di chirurgia Maxillofacciale, Roma 22-24/4/2009.

64.  Marchesi G, Cadenaro M, Breschi L, Antoniolli F, Tay FR, Di Lenarda R, Pashley DH. “Influence of chlorexidine on the E-modulus of experimental resins.” J Dent Res 88 (spec Iss A). Annual meeting of The International Association for Dental Research. Miami FL USA.

65.  Marchesi G, Cadenaro M, Di Lenarda R, Breschi. Bond strenght of  Post Luted with different Self-adhesive Resin Cements. Annual meeting of the Accademy Dental Materials. Portland Oregon USA 29-31/10/2009

66.  Marchesi G. Analysis of aging and stability of bonded interface in dentistry. Poster 2° Workshop of the SFB 762-Wittenberg, Germany 10-11/09/2009.

67.  ORAL:      “Local BDNF delivery by means of laser tweezers to stimulate hippocampal neurons signalling” Elisa D’Este, Gabriele Baj, Paolo Beuzer, Enrico Ferrari, Federica Tavano, Enrico Tongiorgi, Dan Cojoc; ICTP-Introduction to Optofluidics

68.   ORAL: “High spatial resolution BDNF delivery by means of laser tweezers to stimulate hippocampal neurons signalling”; Elisa D’Este, Gabriele Baj, Paolo Beuzer, Enrico Ferrari, Federica Tavano, Enrico Tongiorgi, Dan Cojoc; EBSA 2009

69.   ORAL: “High Resolution Drug Delivery by Optical Tweezers Microscopy” Elisa D’Este, Gabriele Baj, Paolo Beuzer, Enrico Ferrari, Federica Tavano, Enrico Tongiorgi, Dan Cojoc; Super and High Resolution Imaging 2009

70.   POSTER: “Optical Tweezers as means to stimulate hippocampal neurons with BDNF coated beads”; Elisa D’Este, Gabriele Baj, Paolo Beuzer, Enrico Ferrari, Federica Tavano, Enrico Tongiorgi, Dan Cojoc; Nanobioviews-2nd international symposium on Optical Tweezers in life sciences; Award best poster Optical Tweezers

71.  Corona G, Elia C, Casetta B and Toffoli G. Liquid Chromatography/Tandem Mass Spectrometry Method To Rapid Asses the Irinotecan Metabolic Phenotype. Mass Spec Europe 5-6 November 2009, Barcelona, Spain

72.  G.Sciuto, R.Muscia – Multiobjective optimization of intracoronary stents by genetic algorithm. 13th international research/expert conference, Trends in the development of machinery and associated technology, TMT 2009, Hammameth, Tunisia.

73.  R.Muscia, G.Sciuto – A method for performing quality comparisons of Rzeppa joints. 13th international research/expert conference, Trends in the development of machinery and associated technology, TMT 2009, Hammameth, Tunisia.

74.  1. Poster: “High spatial resolution BDNF delivery by means of laser tweezers to stimulate hippocampal neurons signalling”; Elisa D’Este, Gabriele Baj, Paolo Beuzer, Enrico Ferrari, Federica Tavano, Enrico Tongiorgi, Dan Cojoc; EBSA 2009

75.  Poster: “High Resolution Drug Delivery by Optical Tweezers Microscopy” Elisa D’Este, Gabriele Baj, Paolo Beuzer, Enrico Ferrari, Federica Tavano, Enrico Tongiorgi, Dan Cojoc; Super and High Resolution Imaging 2009

76.  Poster: “Optical Tweezers as means to stimulate hippocampal neurons with BDNF coated beads”; Elisa D’Este, Gabriele Baj, Paolo Beuzer, Enrico Ferrari, Federica Tavano, Enrico Tongiorgi, Dan Cojoc; Nanobioviews-2nd international symposium on Optical Tweezers in life sciences

77.  “FARMACOGENETICA DELLA CARDIOTOSSICITÀ DA ANTRACICLINE”, Chiara Zanusso and Giuseppe Toffoli, La gestione delle problematiche” at Napoli on March 25-26, 2009.

78.  “NANOTECHNOLOGIES AND ONCOLOGY: PHARMACOKINETICS AND PHARMACOGENOMICS TO OPTIMIZE THE ANTITUMOR THERAPIES”, Chiara Zanusso, Erika Cecchin, Paola Biason, Elena De Mattia, Franca Sartor and Giuseppe Toffoli, 2nd Phd workshop 10th/11 September 2009, Wittenberg.

 

Patents

 

79.  Italian Patent FI2007A0000179 “Catalizzatori per la produzione di gas di sintesi da reforming di idrocarburi  o alcoli comprendenti un supporto in ZnO e loro uso” ; Inventors: Paolo BERT, Stefano CATANORCHI, Paolo FORNASIERO, Mauro GRAZIANI, Barbara LORENZUT, Hamish MILLER, Tiziano MONTINI, Marina RAGNOLI, Adriana SCAFFIDI, Alessandro TAMPUCCI.

80.  Materiali nanocompositi basati su nanoparticelle metalliche stabilizzate con polisaccaridi a struttura ramificata (Andrea Travan, Ivan Donati, Eleonora Marsich, Sergio Paoletti, Brevetto 8853 PTIT)

81.  Materiali nanocompositi formati da una matrice polisaccaridica e nanoparticelle metalliche, loro preparazione ed uso (Andrea Travan, Ivan Donati, Eleonora Marsich, Sergio Paoletti, Brevetto 8981 PTIT)

82.  Nanocomposite materials based on metallic nanoparticles stabilized with branched polysaccharides (Andrea Travan, Ivan Donati, Elonora Marsich, Sergio Paoletti). PCT Patent extension (2009)

83.  Three-dimensional nanocomposite materials consisting of a polysaccharidic matrix and metallic nanoparticles, preparation and use thereof (Andrea Travan, Ivan Donati, Elonora Marsich, Sergio Paoletti). PCT Patent extension (2009)